Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680615 | 0.96 | MEN1 (0.56) | MEN1KMT2ALMNAHTTKDM4E | |
| SCHEMBL6666691 | 0.96 | ADRB2 (0.48) | MEN1KMT2ALMNAADRB2ADRB3 | |
| SCHEMBL6700387 | 0.90 | ADRB2 (0.55) | MEN1KMT2ALMNAHTTADRB2 | |
| SCHEMBL6678332 | 0.78 | LMNA (0.53) | MEN1KMT2ALMNAHTTKDM4E | |
| SCHEMBL6663592 | 0.78 | ADRB2 (0.50) | KMT2AHTTADRB2ADRB3ADRB1 | |
| SCHEMBL6663218 | 0.77 | KMT2A (0.52) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL27978782 | 0.74 | LMNA (0.65) | MEN1KMT2ALMNAHTTKDM4E | |
| SCHEMBL16293270 | 0.74 | LMNA (0.64) | MEN1KMT2ALMNAADRB2ADRB3 | |
| SCHEMBL6836170 | 0.72 | KMT2A (0.51) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL6836276 | 0.72 | ADRB2 (0.60) | MEN1KMT2ALMNAHTTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014850-A2 | SUBSTITUTED AMINOPYRIMIDINES AS NEUROKININ ANTAGONISTS | PREDIX PHARMACEUTICALS HOLDINGS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |