SCHEMBL666832

SCHEMBL666832

CCCC=C(C#N)C(=O)OOC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.38
ALDH1A1 P00352 7/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.32
NPC1 O15118 4/20 0.31
RAB9A P51151 4/20 0.31
SMN1; SMN2 Q16637 4/20 0.31
NPSR1 Q6W5P4 3/20 0.31
MAPT P10636 4/20 0.31
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
LMNA P02545 2/20 0.31
USP2 O75604 2/20 0.31
GAA P10253 2/20 0.31
KDM4E B2RXH2 3/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTP4A1 Q93096 1/20 0.31
MIF P14174 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL540753 0.90 EP300 (0.37) CYP2C9ALDH1A1PKMHTTTSHR
SCHEMBL20261951 0.87 EP300 (0.46) CYP2C9NPSR1MAPTMEN1KMT2A
SCHEMBL4135131 0.85 CYP2C9 (0.40) CYP2C9ALDH1A1PKMHTTTSHR
SCHEMBL17859724 0.85 CYP2C9 (0.40) CYP2C9ALDH1A1PKMHTTTSHR
SCHEMBL27679283 0.85 CYP2C9 (0.40) CYP2C9ALDH1A1PKMHTTTSHR
SCHEMBL29045740 0.84 CYP2C9 (0.40) CYP2C9ALDH1A1PKMHTTTSHR
SCHEMBL27913452 0.84 CYP2C9 (0.37) CYP2C9ALDH1A1TSHRNPC1RAB9A
SCHEMBL29372874 0.83 CYP2C9 (0.36) CYP2C9ALDH1A1TSHR
SCHEMBL5561382 0.82 CYP2C9 (0.33) CYP2C9ALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL8569025 0.80 CYP2C9 (0.59) CYP2C9ALDH1A1PKMHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056626-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2010-03-04 US claimed
EP-2081567-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES Metis S.r.l. (IT) 2009-07-29 EP claimed
WO-2008059541-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2008-05-22 WO claimed
CN-113874459-B Flexible photocurable cyanoacrylate compositions 汉高股份有限及两合公司 2023-07-04 CN disclosed
US-9402762-B2 Methods and devices for conduit occlusion FEMASYS INC. 2016-08-02 US disclosed
US-9220880-B2 Methods and devices for delivery of compositions to conduits FEMASYS INC. (US) 2015-12-29 US disclosed
US-20150068531-A1 METHODS AND DEVICES FOR CONDUIT OCCLUSION FEMASYS INC. (US) 2015-03-12 US disclosed
US-8726906-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2014-05-20 US disclosed
US-20130220335-A1 Methods and Devices for Conduit Occlusion FEMASYS INC. (US) 2013-08-29 US disclosed
US-20130225977-A1 Methods and Devices for Delivery of Compositions to Conduits FEMASYS INC. (US) 2013-08-29 US disclosed
US-8336552-B2 Methods and devices for conduit occlusion FEMASYS INC. (US) 2012-12-25 US disclosed
WO-2008059541-A1 COSMETIC PRODUCT FOR THE TREATMENT OF CICATRICIAL TISSUES METIS S.R.L. (IT) 2008-05-22 WO disclosed
EP-1838353-A2 TOPICAL ADMINISTRATION PERMITTING PROLONGED EXPOSURE OF TARGET CELLS TO THERAPEUTIC AND PROPHYLACTIC NUCLEIC ACIDS Introgen Therapeutics, Inc. (US) 2007-10-03 EP disclosed
US-20070066552-A1 Topical administration permitting prolonged exposure of target cells to therapeutic and prophylactic nucleic acids INTROGEN THERAPEUTICS, INC. 2007-03-22 US disclosed
WO-2006079014-A2 TOPICAL ADMINISTRATION PERMITTING PROLONGED EXPOSURE OF TARGET CELLS TO THERAPEUTIC AND PROPHYLACTIC NUCLEIC ACIDS INTROGEN THERAPEUTICS, INC. (US) 2006-07-27 WO disclosed
US-6723114-B2 CONTAINING ETHYLENE GLYCOL OXALATE COPOLYMER; BIOABSORBABLE OR BIODEGRADABLE; REDUCED REACTIONS AND FOREIGN BODY RESPONSES POLY-MED, INC. 2004-04-20 US disclosed
US-6699940-B2 Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom POLY MED, INC. 2004-03-02 US disclosed
US-20030105256-A1 Cyanoacrylate-capped heterochain polymers and tissue adhesives and sealants therefrom POLY-MED, INC. 2003-06-05 US disclosed
US-20020116026-A1 Polyester/cyanoacrylate tissue adhesive formulations POLY-MED, INC. 2002-08-22 US disclosed
US-6299631-B1 USEFUL AS TISSUE ADHESIVE/SEALANTS, HEMOSTATIC AGENTS, AND AS A MEANS FOR PATCHING OR ANASTOMIC COUPLING OF DAMAGED ORGANS; BIOABSORPTION POLY-MED, INC. 2001-10-09 US disclosed