SCHEMBL540753

SCHEMBL540753

CCCCC=C(C#N)C(=O)OOC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.37
CYP2C9 P11712 2/20 0.36
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 2/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
SLC16A3 O15427 2/20 0.32
SLC16A1 P53985 2/20 0.32
EGFR P00533 1/20 0.31
GRIK1 P39086 1/20 0.31
ALDH1A1 P00352 3/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20261951 0.94 EP300 (0.46) EP300CYP2C9LMNAPOLBMEN1
SCHEMBL666832 0.90 CYP2C9 (0.38) CYP2C9LMNASMN1; SMN2KDM4EPOLB
SCHEMBL5560343 0.86 KDM4E (0.38) EP300CYP2C9LMNASMN1; SMN2KDM4E
SCHEMBL20261959 0.85 CYP2C9 (0.38) EP300CYP2C9LMNASMN1; SMN2KDM4E
SCHEMBL29372087 0.84 CYP2C9 (0.34) EP300CYP2C9LMNASMN1; SMN2KDM4E
SCHEMBL5560693 0.83 CYP2C9 (0.32) CYP2C9LMNASMN1; SMN2KDM4EPOLB
SCHEMBL4135131 0.82 CYP2C9 (0.40) CYP2C9SMN1; SMN2KDM4EPOLBMEN1
SCHEMBL7167573 0.82 ALDH1A1 (0.33) CYP2C9LMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL11852600 0.82 TSHR (0.36) EP300CYP2C9POLBMEN1MAPT
SCHEMBL11852605 0.82 TSHR (0.36) EP300CYP2C9POLBMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10471174-B2 Cyanoacrylate medical adhesive and preparation method and use thereof Shen, Wei (CN) 2019-11-12 US claimed
EP-3335738-B1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN WEI (CN) 2019-11-06 EP claimed
EP-3513744-A1 MESH DISPENSER Ethicon, Inc. (US) 2019-07-24 EP claimed
US-20190175782-A1 NOVEL CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF SHEN, WEI (CN) 2019-06-13 US claimed
EP-3335738-A1 NEW TYPE CYANOACRYLATE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Shen, Wei (CN) 2018-06-20 EP claimed
US-9752049-B2 Optically transparent, superhydrophobic, biocompatible thin film coatings and methods for producing same UT-BATTELLE, LLC (US) 2017-09-05 US claimed
US-20150232690-A1 OPTICALLY TRANSPARENT, SUPERHYDROPHOBIC, BIOCOMPATIBLE THIN FILM COATINGS AND METHODS FOR PRODUCING SAME UT-BATTELLE, LLC (US) 2015-08-20 US claimed
US-7932305-B2 Viscous α-cyanoacrylate compositions ETHICON, INC. (US) 2011-04-26 US claimed
EP-2152172-A1 MESH DISPENSER Closure Medical Corporation (US) 2010-02-17 EP claimed
US-20090326095-A1 Viscous alpha-Cyanoacrylate Compositions ETHICON, INC. 2009-12-31 US claimed
WO-2007041143-A2 IMPROVED STABILIZER CYANOACRYLATE FORMULATIONS CLOSURE MEDICAL CORPORATION (US) 2007-04-12 WO claimed
US-20070078207-A1 Stabilizer cyanoacrylate formulations ETHICON, INC. 2007-04-05 US claimed
US-6977278-B1 Cyanoacrylate compositions curable to flexible polymeric materials LOCTITE (R&D) LTD. (IE) 2005-12-20 US claimed
EP-1317294-B1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORP (US) 2005-03-16 EP claimed
WO-2004024467-A2 SURFACE-MOUNTING SYSTEM LOCTITE (R & D) LIMITED (IE) 2004-03-25 WO claimed
EP-1360257-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS Loctite (R & D) Limited (IE) 2003-11-12 EP claimed
EP-1317294-A1 ABSORBABLE ADHESIVE COMPOSITIONS Closure Medical Corporation (US) 2003-06-11 EP claimed
WO-2002053666-A1 CYANOACRYLATE COMPOSITIONS CURABLE TO FLEXIBLE POLYMERIC MATERIALS LOCTITE (R & D) LIMITED (IE) 2002-07-11 WO claimed
US-20020037310-A1 Absorbable adhesive compositions CLOSURE MEDICAL CORPORATION (US) 2002-03-28 US claimed
WO-2002009785-A1 ABSORBABLE ADHESIVE COMPOSITIONS CLOSURE MEDICAL CORPORATION (US) 2002-02-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037310-A1 Absorbable adhesive compositions EPCAM, CDH1, ICAM1 EP300 1437/4885CYP2C9 2061/4885LMNA 1559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.