Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 11/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666206 | 0.87 | CHRM3 (0.53) | CHRM3KMT2AL3MBTL1TP53 | |
| SCHEMBL6663062 | 0.87 | GAA (0.48) | CHRM3KMT2AL3MBTL1TP53ACHE | |
| SCHEMBL6664439 | 0.86 | CHRM3 (0.56) | CHRM3KMT2AL3MBTL1TP53ACHE | |
| SCHEMBL17205165 | 0.85 | TGFBR1 (0.57) | CHRM3KMT2AL3MBTL1TP53ACHE | |
| SCHEMBL6666229 | 0.85 | L3MBTL1 (0.51) | CHRM3KMT2AL3MBTL1TP53TDP1 | |
| SCHEMBL6664448 | 0.84 | TDP1 (0.53) | CHRM3KMT2AL3MBTL1TP53TDP1 | |
| SCHEMBL6663459 | 0.83 | CHRM3 (0.58) | CHRM3KMT2AL3MBTL1ACHEBACE1 | |
| SCHEMBL6664925 | 0.81 | KMT2A (0.56) | CHRM3KMT2AL3MBTL1TP53ACHE | |
| SCHEMBL6668837 | 0.81 | CHRM3 (0.49) | CHRM3KMT2AL3MBTL1TP53TDP1 | |
| SCHEMBL6664428 | 0.78 | CHRM3 (0.51) | CHRM3KMT2AL3MBTL1PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |