Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FES | P07332 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6642515 | 0.99 | FLT4 (0.44) | FLT4CDK2ROCK2MAPK1PIK3CA | |
| SCHEMBL6637577 | 0.86 | NPC1 (0.54) | FLT4CDK2ROCK2MAPK1PIK3CA | |
| SCHEMBL6640114 | 0.82 | CYP3A4 (0.47) | FLT4CDK2ROCK2MAPK1PIK3CA | |
| SCHEMBL21070179 | 0.73 | ROCK2 (0.58) | ROCK2NPC1RAB9ASYKSMN1; SMN2 | |
| SCHEMBL23110235 | 0.73 | ROCK2 (0.45) | ROCK2MAPK1PIK3CAMAPK8MAPK9 | |
| SCHEMBL13456828 | 0.73 | KEAP1 (0.60) | FLT4CDK2ROCK2RAB9AHTT | |
| SCHEMBL23110238 | 0.71 | ROCK2 (0.43) | ROCK2PRMT3NPC1SYKKDM4C | |
| SCHEMBL20280535 | 0.70 | ROCK2 (0.49) | ROCK2PRMT3NPC1RAB9AHTT | |
| SCHEMBL6639749 | 0.70 | ROCK2 (0.55) | ROCK2MAPK1HTTKMT2A | |
| SCHEMBL5447385 | 0.69 | MAPK1 (0.82) | MAPK1PIK3CAMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984967-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR ANALOGUES INHIBITING CYTOMEGALOVIRUS | IAF BIOCHEM INT (CA) | 2004-02-25 | — | — | EP | claimed |
| EP-1037633-B1 | ANTIVIRAL COMPOUNDS | IAF BIOCHEM INT (CA) | 2003-09-10 | — | — | EP | claimed |
| US-5945431-A | VIRICIDE | BIOCHEM THERAPEUTICS INCORPORATED (CA) | 1999-08-31 | — | — | US | disclosed |