Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671834 | 0.91 | ALDH1A1 (0.51) | EGLN1CNR1RAB9ANPC1MAPT | |
| SCHEMBL6199161 | 0.89 | EGLN1 (0.47) | EGLN1RAB9ALMNACYP1A2CYP2D6 | |
| SCHEMBL6667789 | 0.84 | MAPT (0.56) | EGLN1RAB9ANPC1MAPTLMNA | |
| SCHEMBL6200449 | 0.80 | PTGER4 (0.48) | EGLN1LMNAALDH1A1CYP1A2GAA | |
| SCHEMBL6199742 | 0.79 | EGLN1 (0.51) | EGLN1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL6199469 | 0.76 | EGLN1 (0.48) | EGLN1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL6199118 | 0.76 | EGLN1 (0.47) | EGLN1RAB9ANPC1MAPTLMNA | |
| SCHEMBL6196111 | 0.76 | EGLN1 (0.47) | EGLN1RAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL6198892 | 0.76 | NR3C1 (0.48) | EGLN1RAB9ANPC1MAPTLMNA | |
| SCHEMBL6199043 | 0.75 | EGLN1 (0.45) | EGLN1LMNAALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |