Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.46 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665348 | 0.93 | SMO (0.44) | SMOEIF2AK3MAPTRAB9ALRRK2 | |
| SCHEMBL6667958 | 0.93 | SMO (0.44) | SMOEIF2AK3AVPR2AVPR1ACYP11B1 | |
| SCHEMBL6803877 | 0.92 | SMO (0.47) | SMOEIF2AK3MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6665157 | 0.88 | SMO (0.49) | SMOEIF2AK3RAB9AHTTAVPR2 | |
| SCHEMBL6663993 | 0.88 | EIF2AK3 (0.50) | SMOEIF2AK3RAB9ACYP11B1CYP11B2 | |
| SCHEMBL6664314 | 0.88 | SMO (0.47) | SMOEIF2AK3HTTAVPR2AVPR1A | |
| SCHEMBL6661936 | 0.88 | SMO (0.47) | SMOEIF2AK3MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6664878 | 0.88 | EIF2AK3 (0.48) | SMOEIF2AK3MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6664409 | 0.87 | EIF2AK3 (0.48) | SMOEIF2AK3MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6809248 | 0.87 | SMO (0.56) | SMOEIF2AK3HTTALDH1A1AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |