Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | THPO | P40225 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712841 | 1.00 | CES2 (0.36) | CES2ALDH1A1TP53HSD17B10BLM | |
| SCHEMBL22325195 | 1.00 | CES2 (0.36) | CES2ALDH1A1TP53HSD17B10BLM | |
| SCHEMBL30661132 | 1.00 | CES2 (0.36) | CES2ALDH1A1TP53HSD17B10BLM | |
| SCHEMBL2010713 | 0.97 | CES2 (0.37) | CES2ALDH1A1TP53HSD17B10BLM | |
| SCHEMBL23875143 | 0.89 | CES2 (0.40) | CES2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2293384 | 0.89 | CES2 (0.40) | CES2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL22266204 | 0.89 | CES2 (0.40) | CES2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL6103881 | 0.89 | MEN1 (0.55) | CES2ALDH1A1TP53HSD17B10MEN1 | |
| SCHEMBL3082724 | 0.89 | MEN1 (0.55) | CES2ALDH1A1TP53HSD17B10MEN1 | |
| SCHEMBL2639316 | 0.89 | CES2 (0.31) | CES2ALDH1A1TP53HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910331-B1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-0910331-A4 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-11-03 | — | — | EP | claimed |
| EP-0910331-A1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | claimed |
| US-5834513-A | TOPICAL COMPOSITION FOR TREATING SKIN CONDITIONS CHARACTERIZED BY ABNORMAL DESQUAMATION | AVON PRODUCTS, INC. (US) | 1998-11-10 | — | — | US | claimed |
| WO-1997039726-A1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-10-30 | — | — | WO | claimed |
| US-9828341-B2 | Dendritic core compounds | VICTORIA LINK LIMITED (NZ) | 2017-11-28 | — | — | US | disclosed |
| US-20150291522-A1 | DENDRITIC CORE COMPOUNDS | CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) | 2015-10-15 | — | — | US | disclosed |
| EP-0910331-B1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0910331-A4 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 1999-11-03 | — | — | EP | disclosed |
| US-5932229-A | TOPICAL COMPOUNDS | AVON PRODUCTS, INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0910331-A1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5834513-A | TOPICAL COMPOSITION FOR TREATING SKIN CONDITIONS CHARACTERIZED BY ABNORMAL DESQUAMATION | AVON PRODUCTS, INC. (US) | 1998-11-10 | — | — | US | disclosed |
| WO-1997039726-A1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291522-A1 | DENDRITIC CORE COMPOUNDS | FLOT1, DBN1, DCTN3 | CES2 1396/4885ALDH1A1 3695/4885TP53 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.