SCHEMBL6668655

SCHEMBL6668655

Oc1cc(O)c2ccccc2c1/N=N/c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.61
MPL P40238 3/20 0.58
MEN1 O00255 6/20 0.50
KMT2A Q03164 6/20 0.50
MAPT P10636 5/20 0.50
LMNA P02545 2/20 0.50
RAB9A P51151 2/20 0.50
USP2 O75604 1/20 0.50
IDO1 P14902 1/20 0.50
TDP1 Q9NUW8 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
HSP90AA1 P07900 2/20 0.49
CASP3 P42574 2/20 0.49
SENP7 Q9BQF6 2/20 0.49
SENP6 Q9GZR1 2/20 0.49
ALPL P05186 1/20 0.49
ALPI P09923 1/20 0.49
GAA P10253 1/20 0.49
ALPG P10696 1/20 0.49
RECQL P46063 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668807 1.00 THRB (0.61) THRBMPLMEN1KMT2AMAPT
SCHEMBL6666444 0.98 THRB (0.59) THRBMPLMEN1KMT2AMAPT
SCHEMBL6666447 0.98 THRB (0.59) THRBMPLMEN1KMT2AMAPT
SCHEMBL8430279 0.84 THRB (0.56) THRBMPLMEN1KMT2AMAPT
SCHEMBL15822833 0.80 THRB (0.51) THRBMPLMEN1KMT2AMAPT
SCHEMBL8428510 0.80 MPL (0.54) THRBMPLMEN1KMT2AMAPT
SCHEMBL11317046 0.78 MEN1 (0.58) THRBMEN1KMT2AMAPTLMNA
SCHEMBL11629954 0.78 MEN1 (0.58) THRBMEN1KMT2AMAPTLMNA
SCHEMBL8689441 0.77 THRB (0.49) THRBMPLMEN1KMT2AMAPT
SCHEMBL8205896 0.77 THRB (0.60) THRBMPLMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452338-A1 Patterned dichroic security features Eidgenössische Technische Hochschule (ETH) (CH) 2004-09-01 EP disclosed