Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MTTP | P55157 | 2/20 | 0.38 |
| ▸ | APOB | P04114 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670014 | 0.91 | EIF2AK3 (0.45) | EIF2AK3HTR2CHTR2BCYP11B1CYP11B2 | |
| SCHEMBL6664165 | 0.89 | EIF2AK3 (0.46) | EIF2AK3HTR2CHTR2BCYP11B1CYP11B2 | |
| SCHEMBL6662151 | 0.88 | HTR2A (0.48) | EIF2AK3HTR2CHTR2BSMOHTR2A | |
| SCHEMBL6664668 | 0.87 | HTR2C (0.49) | EIF2AK3HTR2CHTR2BNPY2RCYP11B1 | |
| SCHEMBL6804744 | 0.86 | HTR2C (0.46) | EIF2AK3HTR2CHTR2BSMOHTR2A | |
| SCHEMBL6670698 | 0.86 | HTR2C (0.48) | EIF2AK3HTR2CHTR2BCYP11B1CYP11B2 | |
| SCHEMBL6667006 | 0.86 | HTR2C (0.49) | EIF2AK3HTR2CHTR2BNPY2RCYP11B1 | |
| SCHEMBL6664663 | 0.85 | EIF2AK3 (0.48) | EIF2AK3HTR2CHTR2BCYP11B1CYP11B2 | |
| SCHEMBL6667820 | 0.84 | SMO (0.50) | EIF2AK3HTR2CHTR2BSMOHTR2A | |
| SCHEMBL6664128 | 0.84 | EIF2AK3 (0.44) | EIF2AK3HTR2CHTR2BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |