Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.48 |
| ▸ | HTR2B | P41595 | 5/20 | 0.48 |
| ▸ | EIF2AK3 | Q9NZJ5 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664128 | 0.92 | EIF2AK3 (0.44) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6668416 | 0.90 | HTR2C (0.49) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6799230 | 0.89 | HTR2C (0.50) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6669300 | 0.88 | LMNA (0.47) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6644163 | 0.86 | MEN1 (0.54) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6667948 | 0.86 | EIF2AK3 (0.45) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6666179 | 0.86 | EIF2AK3 (0.44) | HTR2CHTR2BEIF2AK3HTR2ACYP1A2 | |
| SCHEMBL6669100 | 0.86 | EIF2AK3 (0.45) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6798908 | 0.85 | HTR2C (0.45) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 | |
| SCHEMBL6804070 | 0.85 | MEN1 (0.46) | HTR2CHTR2BEIF2AK3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |