2-Aminopyridine

2-Aminopyridine

SCHEMBL6669260

Nc1ccc(N)nc1.Nc1ccccn1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.70
NOS2 P35228 2/20 0.70
NOS1 P29475 1/20 0.70
PI4KA P42356 1/20 0.70
PI4K2B Q8TCG2 1/20 0.70
PI4K2A Q9BTU6 1/20 0.70
PI4KB Q9UBF8 1/20 0.70
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
MAP4K4 O95819 1/20 0.41
KDM4E B2RXH2 3/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
GLA P06280 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PDPK1 O15530 1/20 0.39
HRH1 P35367 1/20 0.38
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16322246 0.84 NOS3 (0.48) NOS3NOS2NOS1PI4KAPI4K2B
SCHEMBL34048 0.83
SCHEMBL29353771 0.83
2-Aminopyridine SCHEMBL17844 0.83
2-Aminopyridine SCHEMBL2775240 0.83
2-Aminopyridine SCHEMBL9064720 0.83 NOS3 (1.00) NOS3NOS2NOS1PI4KAPI4K2B
2-Aminopyridine SCHEMBL29392931 0.83
Hydrochloric Acid SCHEMBL7654260 0.81
2-Aminopyridine SCHEMBL8135890 0.81 NOS3 (0.94) NOS3NOS2NOS1PI4KAPI4K2B
2-Aminopyridine SCHEMBL70318 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250912-B1 Hair dye composition KPSS KAO GMBH (DE) 2004-09-15 EP claimed
EP-1297818-A2 Hair dye KPSS-Kao Professional Salon Services GmbH (DE) 2003-04-02 EP claimed
EP-1250912-A1 Hair dye composition GOLDWELL GmbH (DE) 2002-10-23 EP claimed