SCHEMBL666947

SCHEMBL666947

NCCCCCCCCC=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.53
TSHR P16473 3/20 0.52
DNM1 Q05193 4/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
LMNA P02545 1/20 0.50
BLM P54132 1/20 0.50
FAAH O00519 2/20 0.46
TRPV1 Q8NER1 1/20 0.46
NFKB1 P19838 1/20 0.44
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL667825 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL6449707 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL259443 1.00
SCHEMBL1682912 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL1960837 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL8812128 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL8812193 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL98074 1.00
SCHEMBL21272039 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1
SCHEMBL8812609 1.00 HIF1A (0.53) HIF1ATSHRDNM1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11965039-B2 Compstatin analogues and their medical uses ZP SPV 3 K/S (DK) 2024-04-23 US claimed
US-11851468-B2 Treatment of neurological diseases UNIVERSITY OF LANCASTER (GB) 2023-12-26 US claimed
EP-4272751-A2 COMPSTATIN ANALOGUES AND THEIR MEDICAL USES ZP SPV 3 K/S (DK) 2023-11-08 EP claimed
US-20230192770-A1 COMPSTATIN ANALOGUES AND THEIR MEDICAL USES ZEALAND PHARMA A/S (DK) 2023-06-22 US claimed
US-11382956-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2022-07-12 US claimed
EP-4021921-A1 COMPSTATIN ANALOGUES AND THEIR MEDICAL USES ZP SPV 3 K/S (DK) 2022-07-06 EP claimed
CN-114630836-A Compstatin analogs and medical uses thereof 西兰制药第三特殊目的公司 2022-06-14 CN claimed
US-20220033457-A1 TREATMENT OF NEUROLOGICAL DISEASES UNIVERSITY OF LANCASTER (GB) 2022-02-03 US claimed
EP-3510044-B1 AMYLIN ANALOGUES ZEALAND PHARMA AS (DK) 2021-11-24 EP claimed
EP-3271381-B1 AMYLIN ANALOGUES ZEALAND PHARMA AS (DK) 2021-09-08 EP claimed
US-20190134159-A1 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2019-05-09 US claimed
EP-3046573-B1 AMYLIN ANALOGUES ZEALAND PHARMA AS (DK) 2018-12-12 EP claimed
US-10071140-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2018-09-11 US claimed
WO-2018104718-A1 TREATMENT OF NEUROLOGICAL DISEASES LANCASTER UNIVERSITY BUSINESS ENTERPRISES LIMITED (GB) 2018-06-14 WO claimed
US-20180071366-A1 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2018-03-15 US claimed
EP-3271381-A1 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2018-01-24 EP claimed
WO-2016146739-A1 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2016-09-22 WO claimed
US-20160272693-A1 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2016-09-22 US claimed
EP-3046573-A2 AMYLIN ANALOGUES Zealand Pharma A/S (DK) 2016-07-27 EP claimed
WO-2015040182-A2 AMYLIN ANALOGUES ZEALAND PHARMA A/S (DK) 2015-03-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11965039-B2 Compstatin analogues and their medical uses C1QBP, C9, VIP HIF1A 4338/4885TSHR 1041/4885DNM1 2638/4885
US-20190134159-A1 AMYLIN ANALOGUES IAPP, GLP1R, AMY2A HIF1A 3708/4885TSHR 1307/4885DNM1 3928/4885
US-10071140-B2 Amylin analogues IAPP, GLP1R, AMY2A HIF1A 3708/4885TSHR 1307/4885DNM1 3928/4885
US-20160272693-A1 AMYLIN ANALOGUES IAPP, GLP1R, AMY2A HIF1A 3708/4885TSHR 1307/4885DNM1 3928/4885
US-20230192770-A1 COMPSTATIN ANALOGUES AND THEIR MEDICAL USES C1QBP, C9, VIP HIF1A 4338/4885TSHR 1041/4885DNM1 2638/4885
US-20180071366-A1 AMYLIN ANALOGUES IAPP, GLP1R, AMY2A HIF1A 3708/4885TSHR 1307/4885DNM1 3928/4885
US-11382956-B2 Amylin analogues IAPP, GLP1R, AMY2A HIF1A 3708/4885TSHR 1307/4885DNM1 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.