Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025700 | 0.79 | HMGCR (0.56) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL19043007 | 0.76 | FDPS (0.52) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL3457861 | 0.76 | HMGCR (0.52) | FDPSLMNAALDH1A1HMGCRCHRM1 | |
| SCHEMBL7107604 | 0.76 | ALDH1A1 (0.46) | FDPSPDE3ALMNAADRB3PDE4D | |
| Ammonia Solution, Strong SCHEMBL10361614 | 0.74 | HMGCR (0.50) | FDPSLMNAALDH1A1HMGCRCHRM1 | |
| SCHEMBL10361611 | 0.74 | HMGCR (0.50) | FDPSLMNAALDH1A1HMGCRCHRM1 | |
| SCHEMBL10360569 | 0.72 | HMGCR (0.42) | FDPSLMNAALDH1A1HMGCRCHRM1 | |
| Citric Acid SCHEMBL332489 | 0.72 | ALDH1A1 (0.79) | LMNAALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL10903812 | 0.72 | HMGCR (0.48) | FDPSLMNAALDH1A1HMGCRCHRM1 | |
| Citric Acid SCHEMBL10520117 | 0.72 | ALDH1A1 (0.79) | LMNAALDH1A1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55127555-A | — | — | None | — | — | JP | disclosed |
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5854227-A | Therapeutic derivatives of diphosphonates | ELIZANOR BIOPHARMACUETICALS, INC. | 1998-12-29 | — | — | US | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0315952-A2 | Photographic processing agents and a method for processing light-sensitive photographic materials | KONICA CORPORATION (JP) | 1989-05-17 | — | — | EP | disclosed |
| US-4774169-A | AMINOPHOSPHONIC ACIDS AND AMINOCARBOXYLIC ACIDS IN DEVELOPER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-09-27 | — | — | US | disclosed |
| JP-S55127555-A | TREATING METHOD FOR SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | KONISHIROKU PHOTO IND CO LTD | 1980-10-02 | — | — | JP | disclosed |