Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697266 | 0.86 | MEN1 (0.42) | MAPTMEN1KMT2AF2LMNA | |
| SCHEMBL6669753 | 0.81 | MEN1 (0.41) | MAPTMEN1KMT2AF2LMNA | |
| SCHEMBL7937693 | 0.76 | MEN1 (0.41) | MAPTMEN1KMT2AF2LMNA | |
| SCHEMBL7846689 | 0.76 | MEN1 (0.43) | MAPTMEN1KMT2AF2LMNA | |
| SCHEMBL7847389 | 0.76 | MEN1 (0.49) | MAPTMEN1KMT2AF2LMNA | |
| SCHEMBL6699753 | 0.74 | MAPT (0.54) | MAPTMEN1KMT2ATP53RXFP1 | |
| SCHEMBL6698316 | 0.73 | MEN1 (0.47) | MAPTMEN1KMT2A | |
| SCHEMBL6703108 | 0.71 | MEN1 (0.45) | MAPTMEN1KMT2AF2LMNA | |
| SCHEMBL6672976 | 0.71 | LMNA (0.38) | MAPTLMNAGAA | |
| SCHEMBL6699609 | 0.71 | KCNH2 (0.59) | MAPTMEN1KMT2AF2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |