Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199313 | 0.84 | LMNA (0.39) | LMNANR3C1EGLN1SMN1; SMN2THRB | |
| SCHEMBL6672975 | 0.79 | LMNA (0.38) | LMNANR3C1EGLN1SMN1; SMN2THRB | |
| SCHEMBL6198300 | 0.78 | LMNA (0.40) | LMNANR3C1EGLN1SMN1; SMN2THRB | |
| SCHEMBL6666974 | 0.77 | LMNA (0.39) | LMNANR3C1EGLN1THRBCNR2 | |
| SCHEMBL6198141 | 0.76 | EGLN1 (0.47) | LMNANR3C1EGLN1CNR2MAPT | |
| SCHEMBL8122619 | 0.76 | NR3C1 (0.43) | LMNANR3C1EGLN1SMN1; SMN2THRB | |
| SCHEMBL6197986 | 0.76 | EGLN1 (0.49) | LMNANR3C1EGLN1SMN1; SMN2CNR2 | |
| SCHEMBL6197926 | 0.75 | LMNA (0.45) | LMNANR3C1EGLN1SMN1; SMN2THRB | |
| SCHEMBL6671910 | 0.75 | P2RX3 (0.36) | LMNANR3C1EGLN1THRBCNR2 | |
| SCHEMBL6200535 | 0.74 | EGLN1 (0.42) | LMNANR3C1EGLN1SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |