Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440319 | 0.83 | L3MBTL1 (0.43) | MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8124349 | 0.81 | ERN1 (0.41) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8116061 | 0.79 | KDM4E (0.56) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| Alcohol SCHEMBL11089265 | 0.78 | NMT1 (0.46) | KDM4EMAPTMEN1KMT2APKM | |
| SCHEMBL11026111 | 0.78 | MAOB (0.47) | KDM4EMAPTALDH1A1LMNAL3MBTL1 | |
| SCHEMBL23564828 | 0.78 | KDM4E (0.50) | KDM4EMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL25170288 | 0.78 | GABRA1 (0.44) | KDM4EMAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL399518 | 0.77 | HPGD (0.55) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11022900 | 0.77 | DEGS1 (0.55) | KDM4EMAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6149991 | 0.76 | MAPK1 (0.45) | KDM4EMAPTALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |