Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 5/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668109 | 0.86 | FNTA (0.49) | MEN1KMT2ACDC25ACACNA1GCACNA1H | |
| SCHEMBL1751915 | 0.76 | CDC25A (0.50) | MEN1KMT2ACDC25ACACNA1GCACNA1H | |
| SCHEMBL29385257 | 0.63 | MEN1 (0.61) | MEN1KMT2ACACNA1GCACNA1HCACNA1I | |
| SCHEMBL10686463 | 0.63 | KMT2A (0.75) | MEN1KMT2AKDM4EMAPK1POLB | |
| SCHEMBL6825068 | 0.62 | CACNA1G (0.55) | MEN1KMT2ACACNA1GCACNA1HCACNA1I | |
| SCHEMBL19750334 | 0.62 | KMT2A (0.63) | MEN1KMT2AEP300CREBBPMAPK1 | |
| SCHEMBL30345008 | 0.62 | EP300 (0.48) | MEN1KMT2ACDC25ACACNA1GCACNA1H | |
| SCHEMBL25049799 | 0.62 | KMT2A (0.77) | MEN1KMT2AKDM4EMAPK1POLB | |
| SCHEMBL13434089 | 0.62 | KMT2A (0.77) | MEN1KMT2AKDM4EMAPK1POLB | |
| SCHEMBL1701279 | 0.61 | KMT2A (0.76) | MEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324985-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2004-10-06 | — | — | EP | claimed |
| EP-1324985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2002028831-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-04-11 | — | — | WO | claimed |
| EP-1324985-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1324985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028831-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-04-11 | — | — | WO | disclosed |