Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668109 | 0.79 | FNTA (0.49) | CDC25ACACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL6669921 | 0.76 | MEN1 (0.42) | CDC25ACACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL29385257 | 0.74 | MEN1 (0.61) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL6825068 | 0.73 | CACNA1G (0.55) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL30345008 | 0.73 | EP300 (0.48) | CDC25ACACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL7741006 | 0.73 | TSHR (0.47) | CDC25AMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL38661561 | 0.71 | PARK7 (0.52) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL7611369 | 0.71 | ALDH1A1 (0.77) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL7611374 | 0.71 | ALDH1A1 (0.77) | CACNA1GCACNA1HCACNA1IMEN1KMT2A | |
| SCHEMBL7828191 | 0.71 | POLB (0.45) | CACNA1GCACNA1HCACNA1IMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572647-B1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-1572647-B1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8710093-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE Ludwigshafen (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2666772-A1 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-7968730-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | CIBA CORPORATION | 2006-03-16 | — | — | US | disclosed |
| EP-1572647-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | Ciba SC Holding AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056769-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | CDC25A 1402/4885CACNA1G 3404/4885CACNA1H 3501/4885 |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | PNMT, HNMT, MAOA | CDC25A 1434/4885CACNA1G 3008/4885CACNA1H 3166/4885 |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | CDC25A 1402/4885CACNA1G 3404/4885CACNA1H 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.