Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.48 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669190 | 0.89 | GNRHR (0.47) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6645028 | 0.86 | FPR1 (0.48) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6673483 | 0.85 | FPR1 (0.43) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL4863039 | 0.84 | GNRHR (0.50) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6638236 | 0.83 | FPR1 (0.49) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6642699 | 0.82 | GNRHR (0.48) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6666665 | 0.81 | FPR1 (0.46) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6667029 | 0.81 | GNRHR (0.47) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL6639154 | 0.81 | GNRHR (0.47) | GNRHRFPR1GPR183GPR119S1PR4 | |
| SCHEMBL4862095 | 0.80 | GNRHR (0.48) | GNRHRFPR1GPR183GPR119S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401427-A4 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMA (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1401427-A2 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | Agouron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098363-A2 | NON-PEPTIDE GnRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |