Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889371 | 0.91 | — | — | |
| SCHEMBL13788528 | 0.81 | ADRA1A (0.41) | LDHASRRTSHRADRA1ASOAT1 | |
| SCHEMBL5597209 | 0.75 | KDM4E (0.48) | TSHRADRA1ASOAT1KDM4EMAPK1 | |
| Aceturic Acid SCHEMBL42918 | 0.73 | CTH (0.52) | LDHASRRTSHRADRA1AKDM4E | |
| Aceturic Acid SCHEMBL5876 | 0.73 | — | — | |
| SCHEMBL9301791 | 0.73 | PHF8 (0.56) | TSHRADRA1ASOAT1KDM4EMAPK1 | |
| Aceturic Acid SCHEMBL10710298 | 0.71 | CTH (0.50) | LDHASRRTSHRADRA1AKDM4E | |
| Aceturic Acid SCHEMBL2120015 | 0.71 | — | — | |
| Aceturic Acid SCHEMBL9438413 | 0.71 | — | — | |
| Aceturic Acid SCHEMBL31614105 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069118-B1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6506903-B1 | By reacting 4-methylthiazole with N-halosuccinimide in solvent in presence of 2,2-azobisisobutyronitrile; halogenation, catalysis | SHIONOGI & CO., LTD. (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1069118-A1 | PROCESS FOR PRODUCING 4-THIAZOLYLMETHYL DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |