Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Scyllitol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Inositol SCHEMBL6670311 | 1.00 | MEN1 (0.36) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL1683101 | 0.87 | KMT2A (0.48) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL1683106 | 0.87 | KMT2A (0.48) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Inositol SCHEMBL9018781 | 0.79 | SLC1A1 (0.48) | KMT2AGSRSLC1A1SLC7A5 | |
| Serine SCHEMBL2812861 | 0.77 | SLC1A1 (0.50) | KMT2AGSRSLC1A1SLC7A5 | |
| Inositol SCHEMBL3339578 | 0.77 | SLC1A1 (0.50) | KMT2AGSRSLC1A1SLC7A5 | |
| Inositol SCHEMBL21243345 | 0.77 | SLC1A1 (0.50) | KMT2AGSRSLC1A1SLC7A5 | |
| Serine SCHEMBL2812858 | 0.77 | SLC1A1 (0.50) | KMT2AGSRSLC1A1SLC7A5 | |
| Ornithine Aketoglutarate SCHEMBL29232510 | 0.76 | GSR (0.58) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Inositol SCHEMBL21296266 | 0.74 | CPT2 (0.37) | LMNASLC1A1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743017-B1 | Application of phospholipases in animal feed | DSM IP ASSETS BV (NL) | 2004-09-29 | — | — | EP | disclosed |