SCHEMBL6670320

SCHEMBL6670320

CCCCCCCCCCCCOc1ccc2c(O)cc(O)c(N=Nc3ccc(N=Nc4ccccc4)cc3)c2c1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.43
PTPN11 Q06124 1/20 0.42
NR5A1 Q13285 1/20 0.42
PPARA Q07869 1/20 0.41
LTA4H P09960 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA10 Q9GZZ6 1/20 0.41
CHRNA9 Q9UGM1 1/20 0.41
CNR2 P34972 2/20 0.40
FAAH O00519 9/20 0.40
ALPL P05186 1/20 0.40
ALPG P10696 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6670318 1.00 KCNH2 (0.43) KCNH2PTPN11NR5A1PPARALTA4H
SCHEMBL6665449 0.85 KCNH2 (0.54) KCNH2PTPN11NR5A1PPARALTA4H
SCHEMBL6665450 0.85 KCNH2 (0.54) KCNH2PTPN11NR5A1PPARALTA4H
SCHEMBL6681017 0.80 HPGD (0.44) ALPLALPG
SCHEMBL6667583 0.80 KCNH2 (0.48) KCNH2CNR2ALPLALPG
SCHEMBL6667586 0.80 KCNH2 (0.48) KCNH2CNR2ALPLALPG
SCHEMBL13417485 0.78 LTA4H (0.64) KCNH2NR5A1PPARALTA4HCHRNA7
SCHEMBL19281444 0.78 LTA4H (0.64) KCNH2NR5A1PPARALTA4HCHRNA7
SCHEMBL1984435 0.78 LTA4H (0.64) KCNH2NR5A1PPARALTA4HCHRNA7
SCHEMBL4942746 0.78 LTA4H (0.64) KCNH2NR5A1PPARALTA4HCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452338-A1 Patterned dichroic security features Eidgenössische Technische Hochschule (ETH) (CH) 2004-09-01 EP disclosed