Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | BLK | P51451 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667583 | 1.00 | KCNH2 (0.48) | KCNH2ALPLALPGTHRBCHUK | |
| SCHEMBL11745835 | 0.82 | SMPD1 (0.51) | KCNH2CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL11745839 | 0.82 | SMPD1 (0.51) | KCNH2CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL4129980 | 0.80 | MEN1 (0.48) | KCNH2THRBCHUKDAPK3JAK2 | |
| SCHEMBL6670318 | 0.80 | KCNH2 (0.43) | KCNH2ALPLALPGCNR2 | |
| SCHEMBL6670320 | 0.80 | KCNH2 (0.43) | KCNH2ALPLALPGCNR2 | |
| SCHEMBL6663874 | 0.79 | CNR1 (0.40) | ALPLALPGTHRBCNR1CNR2 | |
| SCHEMBL6663876 | 0.79 | CNR1 (0.40) | ALPLALPGTHRBCNR1CNR2 | |
| SCHEMBL26172963 | 0.78 | KCNH2 (0.53) | KCNH2ALPLALPGTHRBCHUK | |
| SCHEMBL8428510 | 0.77 | MPL (0.54) | ALPLALPGTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452338-A1 | Patterned dichroic security features | Eidgenössische Technische Hochschule (ETH) (CH) | 2004-09-01 | — | — | EP | disclosed |