Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 3/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668282 | 0.82 | KDM4E (0.40) | HCAR2ALDH1A1KDM4EHPGDPDE2A | |
| SCHEMBL6672288 | 0.80 | HCAR2 (0.41) | HCAR2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL26550995 | 0.70 | PDE3B (0.46) | HCAR2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL6691450 | 0.67 | CHRM2 (0.38) | ALDH1A1HSD17B10TSHRHTTSMN1; SMN2 | |
| SCHEMBL6669696 | 0.66 | KDM4E (0.52) | HCAR2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL5794646 | 0.65 | PGR (0.43) | HCAR2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL25647633 | 0.65 | NQO2 (0.45) | HCAR2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL7028889 | 0.64 | ALDH1A1 (0.38) | HCAR2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7025877 | 0.64 | ALDH1A1 (0.38) | HCAR2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL6390273 | 0.64 | CYP3A4 (0.40) | HCAR2ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | claimed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | claimed |