Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 9/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680689 | 0.78 | PTK2 (0.73) | MAPK8PTK2MAPK10MAPTNPC1 | |
| SCHEMBL6611048 | 0.77 | PTK2 (0.55) | MAPK8PTK2FLT3MAPK10KMT2A | |
| SCHEMBL1726430 | 0.72 | PTK2 (0.59) | MAPK8PTK2MAPK10MAPTNPC1 | |
| SCHEMBL13789353 | 0.71 | MAPK8 (0.73) | MAPK8PTK2FLT3MAPK10MAPT | |
| SCHEMBL24489080 | 0.70 | MAPK8 (0.59) | MAPK8PTK2FLT3MAPK10MAPT | |
| SCHEMBL13270043 | 0.67 | PTK2 (0.71) | MAPK8PTK2MAPK10MAPTNPC1 | |
| SCHEMBL11946878 | 0.67 | PTK2 (0.71) | MAPK8PTK2MAPK10MAPTNPC1 | |
| SCHEMBL5550829 | 0.67 | PTPN2 (0.68) | MAPK8PTK2MAPK10MAPTNPC1 | |
| SCHEMBL1674356 | 0.67 | — | — | |
| SCHEMBL23323409 | 0.66 | PTK2 (0.69) | MAPK8PTK2MAPK10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421074-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003010158-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-02-06 | — | — | WO | disclosed |