Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14937229 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL27813060 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2MAPTTSHR | |
| SCHEMBL6552314 | 0.76 | ESR1 (0.45) | ALDH1A1KDM4EMAPT | |
| SCHEMBL1592408 | 0.76 | GAA (0.47) | ALDH1A1KDM4EMAPT | |
| SCHEMBL27990368 | 0.75 | EPHX1 (0.53) | — | |
| SCHEMBL3677313 | 0.75 | KDM4E (0.52) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL6667162 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4ENPSR1POLB | |
| SCHEMBL27833108 | 0.74 | MAPT (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPTTSHR | |
| SCHEMBL1837900 | 0.73 | ESR1 (0.42) | ALDH1A1KDM4EMAPTTDP1 | |
| Methyl Alcohol SCHEMBL16597701 | 0.73 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |