Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1517504 | 0.89 | PTGS2 (0.43) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL27798204 | 0.85 | NR3C1 (0.40) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL27819484 | 0.85 | NR3C1 (0.40) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL4633834 | 0.82 | PTGS1 (0.50) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL4633827 | 0.80 | NR3C1 (0.45) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL27928023 | 0.80 | PTGS1 (0.48) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL8186747 | 0.77 | CA1 (0.46) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL10834423 | 0.77 | PTGS1 (0.46) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL3801816 | 0.76 | PTGS1 (0.68) | PTGS1PTGS2NR3C1PGRNR3C2 | |
| SCHEMBL5609492 | 0.75 | CA1 (0.44) | PTGS1PTGS2NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072918-A | By the block copolycarbonate ester of compatilizer manufacture silicone-containing | 科思创德国股份有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-106164174-B | Thermoplastic composition | 三菱化学欧洲合资公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-103946268-B | Metallized multilayer articles made of specific polycarbonates having a low coefficient of thermal expansion | 科思创德国股份有限公司 | 2019-02-22 | — | — | CN | disclosed |
| EP-3331935-A1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | Sika Technology AG (CH) | 2018-06-13 | — | — | EP | disclosed |
| WO-2004035654-A1 | METHOD FOR SEPARATING RESIDUAL MONOMERS AND OLIGOMER FROM POLYCARBONATE | BAYER MATERIALSCIENCE AG (DE) | 2004-04-29 | — | — | WO | disclosed |