Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | RARG | P13631 | 3/20 | 0.34 |
| ▸ | HMGCR | P04035 | 3/20 | 0.34 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663900 | 0.83 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5663755 | 0.83 | RXRA (0.36) | RXRAPPARGRARGHMGCRTNFRSF1A | |
| SCHEMBL6683401 | 0.82 | RXRA (0.35) | RXRAPPARGRARGHMGCRTNFRSF1A | |
| SCHEMBL5664303 | 0.80 | RXRA (0.35) | RXRAPPARGRARGHMGCRTNFRSF1A | |
| SCHEMBL5667118 | 0.80 | RXRA (0.35) | RXRAPPARGRARGHMGCRTNFRSF1A | |
| SCHEMBL6672264 | 0.78 | RXRA (0.43) | RXRAPPARGRARGTNFRSF1A | |
| Butane SCHEMBL6671236 | 0.78 | RXRA (0.36) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL9222763 | 0.77 | HMGCR (0.49) | HMGCRTNFRSF1ANR1I2 | |
| SCHEMBL5664315 | 0.74 | ESR1 (0.43) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5664309 | 0.74 | ESR1 (0.43) | RXRAPPARGRARGTNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026243-A2 | THERAPEUTIC USES OF LINEAR KETOPHOSPHONATES | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026242-A2 | SUBSTITUTED KETOPHOSPHONATE INHIBITORS OF TUMOR CELL PROLIFERATION | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |