Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 11/20 | 0.43 |
| ▸ | RARG | P13631 | 5/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663900 | 0.83 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1ARARA | |
| Butane SCHEMBL6671236 | 0.81 | RXRA (0.36) | RXRAPPARGRARGTNFRSF1ARARA | |
| SCHEMBL5664309 | 0.79 | ESR1 (0.43) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5664315 | 0.79 | ESR1 (0.43) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL5663920 | 0.78 | RXRA (0.38) | RXRAPPARGRARGTNFRSF1ARARA | |
| SCHEMBL6671237 | 0.78 | RXRA (0.34) | RXRAPPARGRARGTNFRSF1A | |
| SCHEMBL6680912 | 0.78 | RXRA (0.41) | RXRAPPARGRARGTNFRSF1ARARA | |
| SCHEMBL5662542 | 0.78 | RXRA (0.41) | RXRAPPARGRARGTNFRSF1ARARA | |
| SCHEMBL18556291 | 0.76 | CYP3A4 (0.39) | RXRAPPARGRARGTNFRSF1APTGS2 | |
| SCHEMBL19124038 | 0.76 | CYP3A4 (0.39) | RXRAPPARGRARGTNFRSF1APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026243-A2 | THERAPEUTIC USES OF LINEAR KETOPHOSPHONATES | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | claimed |