Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.75 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.75 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671550 | 0.94 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6669318 | 0.90 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6670823 | 0.89 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6669865 | 0.86 | ADORA3 (0.79) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6669862 | 0.86 | ADORA3 (0.79) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6664819 | 0.86 | ADORA3 (0.86) | ADORA3ADORA1ADORA2AADORA2BALDH1A1 | |
| SCHEMBL6661428 | 0.86 | ADORA3 (0.86) | ADORA3ADORA1ADORA2AADORA2BALDH1A1 | |
| SCHEMBL6671051 | 0.85 | ADORA3 (0.56) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6672998 | 0.85 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6675853 | 0.84 | ADORA3 (0.52) | ADORA3ADORA1ADORA2AADORA2BDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026890-A1 | ACETYLENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026890-A1 | ACETYLENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-04-01 | — | — | WO | disclosed |