Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672998 | 0.91 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6670823 | 0.87 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6671550 | 0.85 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6671051 | 0.85 | ADORA3 (0.56) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6671297 | 0.84 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6261537 | 0.83 | AHCY (0.57) | ADORA3ADORA1ADORA2AADORA2BLMNA | |
| SCHEMBL6669318 | 0.83 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AADORA2BDNPH1 | |
| SCHEMBL6673454 | 0.80 | ADORA3 (0.73) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6672392 | 0.78 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6685672 | 0.77 | ADORA3 (0.71) | ADORA3ADORA1ADORA2AADORA2BPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026890-A1 | ACETYLENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-04-01 | — | — | WO | claimed |
| WO-2004026890-A1 | ACETYLENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-04-01 | — | — | WO | disclosed |