Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | BACE1 | P56817 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30072208 | 1.00 | ACHE (0.65) | ACHEBACE1PPARGFPR2GPR132 | |
| SCHEMBL6129416 | 1.00 | ACHE (0.65) | ACHEBACE1PPARGFPR2GPR132 | |
| SCHEMBL21049245 | 0.98 | ACHE (0.67) | ACHEBACE1PPARGFPR2GPR132 | |
| SCHEMBL23647621 | 0.98 | ACHE (0.67) | ACHEBACE1PPARGFPR2GPR132 | |
| SCHEMBL29256074 | 0.98 | ACHE (0.67) | ACHEBACE1PPARGFPR2GPR132 | |
| SCHEMBL16797495 | 0.91 | ACHE (0.58) | ACHEBACE1PPARGGPR132FAAH | |
| SCHEMBL4759937 | 0.85 | ACHE (0.49) | ACHEBACE1PPARGGPR132FAAH | |
| SCHEMBL649787 | 0.85 | ACHE (0.49) | ACHEBACE1PPARGGPR132FAAH | |
| SCHEMBL4745520 | 0.85 | ACHE (0.49) | ACHEBACE1PPARGGPR132FAAH | |
| SCHEMBL15287182 | 0.85 | ACHE (0.49) | ACHEBACE1PPARGGPR132FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146984-A1 | LYMPH-RELEASING COMPOSITIONS OF FATTY ACIDS AND USES THEREOF FOR LYMPHATIC INCORPORATION AND SYSTEMIC DISEASE TREATMENT | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2023-08-03 | — | — | WO | claimed |
| CN-115768873-A | Viable cell constructs for biosynthesizing dairy products, and products and methods related thereto | 谢恩·吉利亚诺 | 2023-03-07 | — | — | CN | claimed |
| US-20230059978-A1 | LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS | GUILIANO SHAYNE (US) | 2023-02-23 | — | — | US | claimed |
| EP-4087915-A1 | LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS | Guiliano, Shayne (US) | 2022-11-16 | — | — | EP | claimed |
| WO-2021214048-A1 | DUAL INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE AND 5-LIPOXYGENASE | Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) | 2021-10-28 | — | — | WO | claimed |
| WO-2021142241-A1 | LIVE CELL CONSTRUCTS FOR BIOSYNTHETIC MILK PRODUCTION AND RELATED PRODUCTS AND METHODS | GUILIANO SHAYNE (US) | 2021-07-15 | — | — | WO | claimed |
| CN-111454246-A | Soluble epoxide hydrolase inhibitors and uses thereof | X-化学有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-110898050-A | Application of 14, 15-epoxy eicosatrienoic acid in preparing medicament for treating depression and/or anxiety | 南方医科大学 | 2020-03-24 | — | — | CN | claimed |
| CN-107074771-B | Soluble epoxide hydrolase inhibitors and uses thereof | X-化学有限公司 | 2020-03-20 | — | — | CN | claimed |
| US-20180362499-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND USES THEREOF | MIDCAP FINANCIAL TRUST | 2018-12-20 | — | — | US | claimed |
| US-7695927-B2 | Detection of hypertension using glucuronidated metabolic products | DETROIT R & D (US) | 2010-04-13 | — | — | US | claimed |
| WO-2007111601-A1 | DETECTION OF HYPERTENSION USING GLUCURONIDATED METABOLIC PRODUCTS | DETROIT R & D., INC. (US) | 2007-10-04 | — | — | WO | claimed |
| US-20060211064-A1 | Detection of hypertension using glucuronidated metabolic products | DETROIT R & D | 2006-09-21 | — | — | US | claimed |
| US-6916843-B1 | Anti-inflammatory actions of cytochrome P450 expoxygenase-derived eicosanoids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-07-12 | — | — | US | claimed |
| EP-1207877-A4 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | BRIGHAM & WOMENS HOSPITAL (US) | 2004-06-09 | — | — | EP | claimed |
| US-6693130-B2 | UREAS, AMIDES, AND CARBAMATES; DICYCLOHEXYL UREA | REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-02-17 | — | — | US | claimed |
| US-6534282-B2 | Measurement concentration of hydroxyeicostrienoic acid | DETROIT R&D, INC. | 2003-03-18 | — | — | US | claimed |
| US-6440682-B1 | ASSESSING HYPERTENSION BY MEASURING THE AMOUNT OF FREE AND CONJUGATED HYDROXYEICOSATRIENOIC ACIDS (DHETS) AND METABOLITES OF DHETS, WHICH ARE METABOLITES OF ARACHIDONIC ACID EPOXYGENASES AND EPOXIDE HYDROLASES | DETROIT R&D INC. | 2002-08-27 | — | — | US | claimed |
| EP-1207877-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001010438-A1 | ANTI-INFLAMMATORY ACTIONS OF CYTOCHROME P450 EPOXYGENASE-DERIVED EICOSANOIDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2001-02-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362499-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND USES THEREOF | EPHX1, EPHX2, LTA4H | ACHE 875/4885BACE1 904/4885PPARG 940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.