Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.67 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.67 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.67 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684047 | 1.00 | ABCC9 (0.67) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4682262 | 0.90 | LMNA (0.67) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4682799 | 0.85 | ABCC9 (0.82) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4682701 | 0.83 | ABCC9 (0.82) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4682104 | 0.83 | ABCC9 (0.82) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4678811 | 0.83 | ABCC9 (0.82) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4684962 | 0.82 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4684953 | 0.82 | ABCC9 (0.47) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4682133 | 0.80 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8KMT2A | |
| SCHEMBL4682028 | 0.79 | MEN1 (0.55) | ABCC9ABCC8KCNJ11KCNJ8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392655-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002062762-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |