Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671661 | 1.00 | AAK1 (0.36) | AAK1NFKB1NFKB2RELAGLO1 | |
| SCHEMBL12202636 | 0.84 | NFKB1 (0.33) | AAK1NFKB1NFKB2RELAGLO1 | |
| SCHEMBL57433 | 0.82 | NFKB1 (0.32) | AAK1NFKB1NFKB2RELAGLO1 | |
| SCHEMBL10175776 | 0.82 | NFKB1 (0.32) | AAK1NFKB1NFKB2RELAGLO1 | |
| SCHEMBL6688667 | 0.81 | CA1 (0.36) | AAK1 | |
| SCHEMBL6688662 | 0.81 | CA1 (0.36) | AAK1 | |
| SCHEMBL6675216 | 0.80 | DPP4 (0.39) | — | |
| SCHEMBL6675219 | 0.80 | DPP4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL6670921 | 0.79 | DPP4 (0.38) | — | |
| Hydrochloric Acid SCHEMBL6670922 | 0.79 | DPP4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040121965-A1 | Method of treating resistant tumors | WYETH HOLDINGS CORPORATION (US) | 2004-06-24 | — | — | US | disclosed |
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121965-A1 | Method of treating resistant tumors | SLC11A2, VHL, REN | AAK1 4223/4885NFKB1 855/4885NFKB2 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.