SCHEMBL6671753

SCHEMBL6671753

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1ccc(NNC=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.42
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
MAPK1 P28482 5/20 0.42
SMN1; SMN2 Q16637 5/20 0.42
ALDH1A1 P00352 3/20 0.42
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
MAPT P10636 6/20 0.35
HTT P42858 3/20 0.35
UBE2N P61088 2/20 0.35
GLA P06280 1/20 0.35
MITF O75030 1/20 0.35
ACACB O00763 1/20 0.35
KLK7 P49862 5/20 0.34
RAB9A P51151 2/20 0.33
RAD52 P43351 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9282439 0.88 TRPV1 (0.38) NPSR1KMT2AMAPK1ALDH1A1APOBEC3A
SCHEMBL9166429 0.87 NPSR1 (0.43) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL9868418 0.87 NPSR1 (0.48) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL7767160 0.86 NPSR1 (0.45) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL11772726 0.86 SMN1; SMN2 (0.45) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL14564633 0.86 KMT2A (0.46) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL9848197 0.85 SMN1; SMN2 (0.44) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL7040054 0.85 NPSR1 (0.46) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL8014594 0.84 NPSR1 (0.42) NPSR1KMT2AMEN1MAPK1SMN1; SMN2
SCHEMBL14462468 0.84 APOBEC3A (0.41) NPSR1KMT2AMEN1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5372921-A Having imaging and printout layers containing small doped silver halide grains at specified dopant level and third set thereof distributed in printout layer or separate protective layer EASTMAN KODAK COMPANY (US) 1994-12-13 US claimed
US-5279933-A Black and white photography EASTMAN KODAK COMPANY (US) 1994-01-18 US claimed
US-5175073-A High contrast black and white photographic film; containing hydrazide compound EASTMAN KODAK COMPANY (US) 1992-12-29 US claimed
US-4975354-A Silver halide developed in presence of a hydrazone using an aqueous alkaline solution; black and white photography; lithography EASTMAN KODAK COMPANY (US) 1990-12-04 US claimed
EP-1057076-B1 HIGH CONTRAST PHOTOGRAPHIC SILVER HALIDE MATERIAL EASTMAN KODAK CO (US) 2004-09-29 EP disclosed
US-6383711-B1 PHOTOGRAPHIC FILMS WITH SUPPORTS AND SILVER HALIDE EMULSIONS AND HYDROPHILIC COLLOIDS EASTMAN KODAK COMPANY 2002-05-07 US disclosed
EP-0682288-B1 High contrast photographic silver halide material EASTMAN KODAK CO (US) 2001-06-27 EP disclosed
EP-0681208-B1 High contrast photographic silver halide material EASTMAN KODAK CO (US) 2001-05-16 EP disclosed
EP-1057076-A1 HIGH CONTRAST PHOTOGRAPHIC SILVER HALIDE MATERIAL EASTMAN KODAK COMPANY (US) 2000-12-06 EP disclosed
WO-2000038008-A1 HIGH CONTRAST PHOTOGRAPHIC SILVER HALIDE MATERIAL EASTMAN KODAK COMPANY (US) 2000-06-29 WO disclosed
EP-0650086-B1 Method of improving abrasion resistance of photographic silver halide materials KODAK LTD (GB) 1999-12-08 EP disclosed
EP-0774686-B1 High-contrast photographic elements protected against halation EASTMAN KODAK CO (US) 1999-07-21 EP disclosed
EP-0209012-A2 High contrast photographic elements exhibiting reduced pepper fog EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-01-21 EP disclosed
EP-0208514-A2 Silver halide radiation-sensitive photographic materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-01-14 EP disclosed
US-4634661-A SILVER HALIDE EMULSION, ARYLHYDRAZIDE, CARBOXYALKYL SUBSTITUTED 3H-THIAZOLINE-2-THIONE EASTMAN KODAK COMPANY (US) 1987-01-06 US disclosed
US-4618574-A AN ARYLHYDRAZIDE, A POLHYDROXYBENZENE AND A CARBOXYALKYL3H-THIAZOLINE-2-THIONE EASTMAN KODAK COMPANY (US) 1986-10-21 US disclosed
US-H41-H Halftone imaging silver halide emulsions, photographic elements, and processes which employ novel arylhydrazides EASTMAN KODAK COMPANY (US) 1986-04-01 US disclosed
US-4572892-A 1,2,3-TRIAZOLE ANTIFOGGING AGENT; COVERING POWER, BLACK AND WHITE PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1986-02-25 US disclosed
US-4560638-A Halftone imaging silver halide emulsions, photographic elements, and processes which employ novel arylhydrazides EASTMAN KODAK COMPANY (US) 1985-12-24 US disclosed
EP-0032456-A1 Method for high contrast development of photographic elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-07-22 EP disclosed