SCHEMBL9868418

SCHEMBL9868418

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1ccc([O])cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 6/20 0.48
KMT2A Q03164 6/20 0.48
MAPK1 P28482 5/20 0.48
MEN1 O00255 5/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
ALDH1A1 P00352 3/20 0.48
APOBEC3A P31941 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
MAPT P10636 6/20 0.38
HTT P42858 3/20 0.38
UBE2N P61088 2/20 0.38
GLA P06280 1/20 0.38
MITF O75030 1/20 0.38
ACACB O00763 1/20 0.37
KLK7 P49862 4/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
RAD52 P43351 2/20 0.35
RAB9A P51151 2/20 0.35
STAT3 P40763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11772726 0.90 SMN1; SMN2 (0.45) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL7767160 0.90 NPSR1 (0.45) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL14564633 0.90 KMT2A (0.46) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL9848197 0.89 SMN1; SMN2 (0.44) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL7040054 0.89 NPSR1 (0.46) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL9166429 0.88 NPSR1 (0.43) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL6671753 0.87 NPSR1 (0.42) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL8033792 0.87 MEN1 (0.42) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL11002253 0.86 NPSR1 (0.43) NPSR1KMT2AMAPK1MEN1SMN1; SMN2
SCHEMBL11348616 0.86 MAPK1 (0.51) NPSR1KMT2AMAPK1MEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051342-A Sharpness, whiteness FUJI PHOTO FILM CO., LTD. (JP) 1991-09-24 US disclosed