Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.54 |
| ▸ | PGR | P06401 | 11/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671996 | 0.83 | NR3C1 (0.52) | NR3C1NR3C2PGRMTNR1AMTNR1B | |
| SCHEMBL6671994 | 0.79 | NR3C1 (0.72) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1635100 | 0.78 | NR3C1 (0.85) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL27748428 | 0.74 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL1634224 | 0.70 | NR3C2 (0.44) | NR3C1NR3C2PGR | |
| SCHEMBL1633711 | 0.70 | NR3C1 (1.00) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL14340577 | 0.65 | NR3C1 (0.74) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1633555 | 0.64 | NR3C1 (0.74) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL7808561 | 0.64 | MTNR1A (0.61) | NR3C1NR3C2PGRMTNR1AMTNR1B | |
| SCHEMBL14145499 | 0.64 | NR3C1 (0.69) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490062-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082280-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-10-09 | — | — | WO | disclosed |