Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6672015

Cc1cccc(CI)c1C.N

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
TRPA1 O75762 1/20 0.41
ATM Q13315 1/20 0.41
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
GLA P06280 1/20 0.35
STING1 Q86WV6 1/20 0.35
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3975855 0.98 ESR1 (0.44) ESR1ESR2TRPA1ATMTP53
SCHEMBL8575102 0.85 PDCD1 (0.37) ESR1ESR2TRPA1ATMTP53
Ammonia Solution, Strong SCHEMBL9169935 0.78 PON1 (0.31) CYP1A2CYP2A6TSHR
Ammonia Solution, Strong SCHEMBL4439587 0.78 GABRA1 (0.48) ESR1ESR2TRPA1ATMTP53
SCHEMBL395673 0.78 ESR1 (0.44) ESR1ESR2TRPA1ATMTP53
SCHEMBL6547407 0.77 ESR1 (0.47) ESR1ESR2TRPA1ATMTP53
SCHEMBL30231281 0.77 ESR1 (0.47) ESR1ESR2TRPA1ATMTP53
SCHEMBL3306785 0.77 ESR1 (0.47) ESR1ESR2TRPA1ATMTP53
SCHEMBL31083860 0.77
SCHEMBL1422357 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004026352-A1 USE AS BINDER OF ION TRIGGERABLE, VINYL-BASED CATIONIC POLYMERS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2004-04-01 WO claimed