Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648047 | 0.88 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL3758268 | 0.80 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL31560140 | 0.80 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL16115685 | 0.79 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL16138117 | 0.79 | MAPT (0.42) | L3MBTL1ALDH1A1TDP1THRBGAA | |
| SCHEMBL2829001 | 0.77 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1THRBGAAHTT | |
| SCHEMBL3012179 | 0.77 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL6609369 | 0.76 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1CYP3A4ALOX15TDP1 | |
| SCHEMBL18157850 | 0.76 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1THRBGAAHTT | |
| SCHEMBL30369746 | 0.76 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1THRBGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |