SCHEMBL6672089

SCHEMBL6672089

NC(=O)CC[C@H](N)C(=O)OC(=O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.44
ALDH1A1 P00352 2/20 0.42
SLC1A3 P43003 1/20 0.42
SLC1A1 P43005 1/20 0.42
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910535 0.89 ALDH1A1 (0.45) LTA4HALDH1A1SLC1A3SLC1A1KMT2A
SCHEMBL4989084 0.88 LTA4H (0.48) LTA4HALDH1A1SLC1A3SLC1A1ALOX15
SCHEMBL4989088 0.88 LTA4H (0.48) LTA4HALDH1A1SLC1A3SLC1A1ALOX15
Hydrochloric Acid SCHEMBL9188911 0.87 LTA4H (0.47) LTA4HALDH1A1SLC1A3SLC1A1ALOX15
Hydrochloric Acid SCHEMBL7393352 0.87 LTA4H (0.47) LTA4HALDH1A1SLC1A3SLC1A1ALOX15
SCHEMBL7391550 0.83 LTA4H (0.48) LTA4HALDH1A1SLC1A3SLC1A1KMT2A
SCHEMBL4810846 0.82 ALPI (0.53) LTA4HSLC1A3SLC1A1ALOX15BLM
SCHEMBL7272552 0.82 ALDH1A1 (0.47) ALDH1A1SLC1A3SLC1A1KMT2ATSHR
SCHEMBL383649 0.82 ALDH1A1 (0.47) ALDH1A1SLC1A3SLC1A1KMT2ATSHR
SCHEMBL3985411 0.82 SLC7A5 (0.56) LTA4HALDH1A1SLC1A3SLC1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693556-B1 TRANSGLUTAMINASE ORIGINATING IN JAPANESE OYSTER AJINOMOTO KK (JP) 2004-10-06 EP disclosed
EP-0379606-B2 Novel transglutaminase AJINOMOTO KK (JP) 1999-07-28 EP disclosed
US-5736356-A CULTIVATION OF TRANSFORMED CELL AS GELLING AGENT FOR GELATION OF PROTEIN SOLUTION OR SLURRY AJINOMOTO CO., INC. (JP) 1998-04-07 US disclosed
EP-0693556-A1 TRANSGLUTAMINASE ORIGINATING IN JAPANESE OYSTER Ajinomoto Co., Inc. (JP) 1996-01-24 EP disclosed
US-5252469-A Culturing the microorganism in the absence of calcium ion AMANO PHARMACEUTICAL CO., LTD. (JP) 1993-10-12 US disclosed
US-5156956-A Derived from microorganism; catalyzes protein gelation in absence of calcium AJINOMOTO CO., INC. (JP) 1992-10-20 US disclosed
EP-0379606-A1 Novel transglutaminase AJINOMOTO CO., INC. (JP) 1990-08-01 EP disclosed