SCHEMBL6672104

SCHEMBL6672104

N#CC1=COC(=O)C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CUL4A Q13619 1/20 0.40
MAPT P10636 5/20 0.38
MAPK1 P28482 3/20 0.38
LMNA P02545 3/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
HTR2B P41595 1/20 0.38
GAA P10253 2/20 0.37
IDO1 P14902 1/20 0.35
ALDH1A1 P00352 7/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 3/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4323808 0.76 MEN1 (0.40) CUL4AMAPTMAPK1LMNACYP1A2
SCHEMBL2644762 0.72 MAPT (0.42) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL16046136 0.70 MAPT (0.41) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL6486287 0.69 HTR2B (0.39) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL10533506 0.68 MAPT (0.39) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL3865099 0.67 MAPT (0.37) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL13685711 0.66 CUL4A (0.44) CUL4AMAPTMAPK1LMNATP53
SCHEMBL10707636 0.65 MAPT (0.52) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL7159370 0.64 PTPRF (0.36) MAPTMAPK1LMNATP53CYP1A2
SCHEMBL6488239 0.62 CNR2 (0.35) MAPTMAPK1LMNATP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0456148-B1 Filter dyes for photographic elements EASTMAN KODAK CO (US) 1996-07-24 EP claimed
US-5098820-A Coumarin dyes for photographic films EASTMAN KODAK COMPANY (US) 1992-03-24 US claimed
EP-0456148-A1 Filter dyes for photographic elements EASTMAN KODAK COMPANY (US) 1991-11-13 EP claimed
EP-0985968-B1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK CO (US) 2004-10-06 EP disclosed
US-6527977-B2 Solvent dispersion EASTMAN KODAK COMPANY 2003-03-04 US disclosed
US-6455210-B1 SUPPORT, PHOTOTHERMOGRAPHIC IMAGE- RECEIVING LAYERS, AND ANTIHALATION LAYER OR FILTER LAYERS OF A DYE AND A HEXAARYLBIIMIDAZOLE IN A DISPERSION OF A HYDROPHILIC POLYMER EASTMAN KODAK COMPANY 2002-09-24 US disclosed
EP-1217431-A2 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
US-6355386-B1 FOR PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY 2002-03-12 US disclosed
US-20020009656-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2002-01-24 US disclosed
US-6214499-B1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY 2001-04-10 US disclosed
US-6180295-B1 CONTAINING MEROCYANINE DYE EASTMAN KODAK COMPANY 2001-01-30 US disclosed
EP-0985968-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed
EP-0985970-A1 Liquid crystalline filter dyes for imaging elements EASTMAN KODAK COMPANY (US) 2000-03-15 EP disclosed
EP-0456148-B1 Filter dyes for photographic elements EASTMAN KODAK CO (US) 1996-07-24 EP disclosed
US-5098820-A Coumarin dyes for photographic films EASTMAN KODAK COMPANY (US) 1992-03-24 US disclosed
EP-0456148-A1 Filter dyes for photographic elements EASTMAN KODAK COMPANY (US) 1991-11-13 EP disclosed