⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300776 | 0.67 | — | — | |
| SCHEMBL1066236 | 0.61 | ALDH1A1 (0.36) | — | |
| SCHEMBL12927499 | 0.58 | HSD17B10 (0.33) | — | |
| SCHEMBL10632026 | 0.58 | ALDH1A1 (0.33) | — | |
| SCHEMBL12927500 | 0.58 | HSD17B10 (0.33) | — | |
| SCHEMBL12927463 | 0.58 | HSD17B10 (0.33) | — | |
| SCHEMBL4492333 | 0.58 | — | — | |
| SCHEMBL3900486 | 0.56 | — | — | |
| SCHEMBL12927494 | 0.56 | HSD17B10 (0.31) | — | |
| SCHEMBL11463122 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775149-B1 | NOVEL PROTECTING GROUPS AND USE THEREOF IN AN IMPROVED PROCESS FOR OLIGONUCLEOTIDE SYNTHESIS | UNIV COLORADO (US) | 2004-09-22 | — | — | EP | disclosed |
| US-6008400-A | MIXING TRIMETHYLORTHOFORMATE AND AN ALCOHOL IN A SOLVENT TO PRODUCE A REACTION MIXTURE AND REMOVING THE SOLVENT TO YIELD ORTHOESTER REAGENT | REGENTS OF THE UNIVERSITY OF COLORADO, THE | 1999-12-28 | — | — | US | disclosed |
| US-5889136-A | PHOSPHORAMIDITE OLIGONUCLEOTIDE BIOSYNTHESIS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-03-30 | — | — | US | disclosed |