Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672153 | 1.00 | EPHX1 (0.33) | EPHX1MAPK1THRBLMNAGAA | |
| SCHEMBL6696310 | 0.84 | POLA1 (0.36) | EPHX1MAPK1THRBLMNAKMT2A | |
| SCHEMBL6690714 | 0.83 | LMNA (0.37) | EPHX1MAPK1THRBLMNAGAA | |
| SCHEMBL6668056 | 0.83 | MAPK1 (0.39) | MAPK1GAAKMT2AALDH1A1MAPT | |
| SCHEMBL6695866 | 0.83 | NPC1 (0.33) | EPHX1MAPK1THRBLMNAGAA | |
| SCHEMBL6670944 | 0.83 | NPC1 (0.33) | EPHX1MAPK1THRBLMNAGAA | |
| SCHEMBL6670947 | 0.83 | NPC1 (0.33) | EPHX1MAPK1THRBLMNAGAA | |
| SCHEMBL6672693 | 0.82 | MAPK1 (0.38) | MAPK1GAAKMT2AALDH1A1MAPT | |
| SCHEMBL6671395 | 0.82 | ALDH1A1 (0.44) | MAPK1THRBLMNAKMT2AALDH1A1 | |
| SCHEMBL6667440 | 0.82 | MAPK1 (0.35) | MAPK1GAAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019940-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |