Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672237 | 0.86 | NR1H4 (0.33) | MEN1KMT2AMAPK14 | |
| SCHEMBL6987858 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6992928 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6987889 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6668158 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6672672 | 0.80 | NR1H4 (0.34) | MAPK14SMN1; SMN2 | |
| SCHEMBL6991326 | 0.79 | HPGD (0.42) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6991875 | 0.78 | HPGD (0.43) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6985330 | 0.78 | HPGD (0.43) | ALDH1A1HPGDGAAKDM4EGLA | |
| SCHEMBL6991347 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDGAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363887-A1 | SUBSTITUTED QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002070487-A1 | SUBSTITUTED QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-09-12 | — | — | WO | claimed |
| EP-1363887-A1 | SUBSTITUTED QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070487-A1 | SUBSTITUTED QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |