Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.57 |
| ▸ | PLG | P00747 | 3/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674424 | 0.87 | F10 (0.52) | F10PLGF2GPR119NPC1 | |
| SCHEMBL31013899 | 0.85 | GPR119 (0.56) | GPR119HRH3NR1H2NPC1RAB9A | |
| SCHEMBL974703 | 0.83 | GPR119 (0.55) | GPR119HRH3NR1H2NPC1RAB9A | |
| SCHEMBL974823 | 0.82 | GPR119 (0.56) | GPR119HRH3NR1H2NPC1RAB9A | |
| SCHEMBL4915776 | 0.81 | GPR119 (0.53) | GPR119HRH3NR1H2NPC1RAB9A | |
| SCHEMBL974325 | 0.81 | HRH3 (0.60) | GPR119HRH3NR1H2NPC1RAB9A | |
| SCHEMBL6671296 | 0.81 | HRH3 (0.57) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL24628711 | 0.80 | F10 (0.47) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL6674044 | 0.80 | F10 (0.49) | F10PLGF2PRSS1PRSS2 | |
| SCHEMBL3090692 | 0.80 | HRH3 (0.68) | GPR119HRH3NR1H2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |