Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672245 | 0.87 | F10 (0.57) | F10GPR119F2PLGNPC1 | |
| SCHEMBL4915392 | 0.83 | GPR119 (0.52) | F10GPR119SLC2A1NPC1RAB9A | |
| SCHEMBL6673187 | 0.82 | F10 (0.59) | F10GPR119SLC2A1CHEK2NPC1 | |
| SCHEMBL6190651 | 0.80 | F10 (0.56) | F10SLC2A1 | |
| SCHEMBL13097234 | 0.77 | ESR2 (0.56) | F10GPR119 | |
| SCHEMBL6189777 | 0.77 | F10 (0.66) | F10GPR119 | |
| SCHEMBL3892320 | 0.76 | ESR2 (0.56) | GPR119NPC1RAB9A | |
| SCHEMBL26668458 | 0.76 | SLC2A1 (0.59) | GPR119SLC2A1CHEK2 | |
| SCHEMBL3242492 | 0.75 | CHEK2 (0.54) | GPR119SLC2A1CHEK2 | |
| SCHEMBL19833969 | 0.75 | NPC1 (0.47) | F10GPR119CHEK2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035544-A1 | BENZO[D]AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |