Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163000 | 0.87 | SERPINE1 (0.46) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL28444407 | 0.87 | SERPINE1 (0.46) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL1137255 | 0.82 | SERPINE1 (0.46) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL28447050 | 0.82 | SERPINE1 (0.46) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL28446906 | 0.81 | SERPINE1 (0.44) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL15142163 | 0.81 | SERPINE1 (0.44) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL5664340 | 0.81 | SERPINE1 (0.44) | SERPINE1PTPN2PTPN1PTPN11KDM4E | |
| SCHEMBL391922 | 0.77 | SERPINE1 (0.57) | SERPINE1PTPN2PTPN1PTPN11ESR1 | |
| SCHEMBL28031026 | 0.77 | SERPINE1 (0.57) | SERPINE1PTPN2PTPN1PTPN11ESR1 | |
| Water SCHEMBL23067557 | 0.76 | SERPINE1 (0.56) | SERPINE1PTPN2PTPN1PTPN11ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032946-A1 | CUTANEOUS WRINKLE TREATMENT AGENT | BOLDT IRENE (DE) | 2004-04-22 | — | — | WO | disclosed |
| EP-0576936-B1 | Hamamelis dry extract, process for its preparation and its use as a medicine | SCHWABE WILLMAR GMBH & CO (DE) | 1998-11-25 | — | — | EP | disclosed |
| EP-0576936-A1 | Hamamelis dry extract, process for its preparation and its use as a medicine | Dr. Willmar Schwabe GmbH & Co. (DE) | 1994-01-05 | — | — | EP | disclosed |