Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672462 | 1.00 | MEN1 (0.55) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL28175306 | 0.84 | MEN1 (0.71) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL27633061 | 0.84 | MEN1 (0.71) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL9386926 | 0.83 | ANPEP (0.60) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL7268268 | 0.83 | ANPEP (0.60) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL6105902 | 0.83 | ANPEP (0.60) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL27484019 | 0.83 | KMT2A (0.51) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL27577953 | 0.81 | MEN1 (0.49) | MEN1KMT2ACA12CA14CA2 | |
| SCHEMBL12984801 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1CYP2C9RAB9A | |
| SCHEMBL11668813 | 0.78 | KIF11 (0.48) | MEN1KMT2ACA12CA14CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736036-B1 | KININOGEN INHIBITORS | FERRING BV (NL) | 2004-10-13 | — | — | EP | disclosed |
| WO-1995007291-A1 | KININOGEN INHIBITORS | FERRING B.V. (NL) | 1995-03-16 | — | — | WO | disclosed |