Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | MELK | Q14680 | 4/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198291 | 0.81 | NPC1 (0.43) | SLC2A1CNR2EGLN1 | |
| SCHEMBL6197986 | 0.77 | EGLN1 (0.49) | CNR2EGLN1HPGDNR3C1GSK3B | |
| SCHEMBL6198898 | 0.76 | EGLN1 (0.44) | CNR2EGLN1HPGDNR3C1GSK3B | |
| SCHEMBL6200031 | 0.76 | MEN1 (0.41) | CNR2EGLN1HPGDNR3C1 | |
| SCHEMBL6666974 | 0.76 | LMNA (0.39) | CNR2EGLN1NR3C1GSK3BCYP1A2 | |
| SCHEMBL6198141 | 0.75 | EGLN1 (0.47) | CNR2EGLN1HPGDNR3C1GSK3B | |
| SCHEMBL6199189 | 0.75 | EGLN1 (0.49) | CNR2EGLN1HPGDGSK3BPOLA1 | |
| SCHEMBL8122619 | 0.75 | NR3C1 (0.43) | CNR2EGLN1HPGDNR3C1GSK3B | |
| SCHEMBL6198854 | 0.75 | EGLN1 (0.54) | CNR2EGLN1HPGDNR3C1GSK3B | |
| SCHEMBL6199105 | 0.75 | MEN1 (0.49) | CNR2EGLN1ERN1GSK3BPOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |